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TransformStream creates a readable/writable pair with processing logic in between. The transform() function executes on write, not on read. Processing of the transform happens eagerly as data arrives, regardless of whether any consumer is ready. This causes unnecessary work when consumers are slow, and the backpressure signaling between the two sides has gaps that can cause unbounded buffering under load. The expectation in the spec is that the producer of the data being transformed is paying attention to the writer.ready signal on the writable side of the transform but quite often producers just simply ignore it.
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Novo Nordisk said that anyone experiencing side effects is advised to report it to a healthcare provider, as well as to the MHRA's Yellow Card scheme, which is designed to help the agency discover safety issues as soon as possible.
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