Producer: Kate White, Katie Tomsett, Clare Salisbury and Alex Mansfield
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除此之外，目前大多数进展集中在B细胞介导的疾病，但自免疾病谱系广阔，机制复杂。未来的发展需要探索新的靶点。如宾夕法尼亚大学针对IGHV4-34 B细胞受体的CAR-T，能更精准清除致病克隆而保留健康B细胞，并将疗法拓展至T细胞介导或其他免疫细胞紊乱的疾病，如类风湿关节炎等。
Italians said they sympathised with Ukrainians but many questioned Italy's involvement in the conflict. They simply didn't trust their government to protect them from knock-on effects, like rising energy prices or potential reprisals by Russia.